Complex Systems and Computational Biology Approaches to Acute Inflammation, 2nd Edition
Description
2021 / English / 307 pages / PDF / 8,62 MB
This Second Edition expands and updates the vital research covered in its predecessor, presenting multidisciplinary and system-oriented approaches to complex diseases derived from and driven by acute inflammatory response. The chapters in this volume provide an introduction to the different types of computational modeling and how these methods can be applied to inflammatory diseases specific, with a focus on providing readers with a roadmap to integrate mathematical techniques and computational advanced methods of experimental traditional. In this second edition, we cover well-established and emerging modeling methods, especially state-of-the-art machine learning approaches and the integration of data-driven and mechanistic modeling.
This volume introduces the concept of model-based precision medicine as an alternative approach to the current vision of precision medicine, based on leveraging mechanistic computational modeling to decrease the cost while increasing the information value of the data that is obtained.
By presenting the role of computational modeling as an integrated component of the research process, complex systems and computational biology approaches to acute inflammation: a framework for model-based Precision Medicine offers a window into the recent past, present and future of computationally augmented biomedical research.
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